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+86 156 3115 5652
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Mob.:
+86 156 3115 5652
Mob.:
+86 156 3115 5652
E-mail:
thinkdo_calvin@126.com/thinkdochem@126.com
PASP and Its Derivatives
Calcium of polyaspartic acid/Calcium polyaspartate/Polyaspartic acid calcium salt
Polyaspartic acid of calcium is an organic calcium supplement. Polyaspartic acid is an artificially synthesized polyamino acid with good biocompatibility. Structurally speaking, the molecular chain of aspartic acid binds calcium ions, and the molecular chain structure of polyaspartic acid can make calcium more stable in solution and other environments, and this structure is conducive to the absorption and transportation of calcium. Its structure is relatively complex, and it is a form of high molecular weight polymer combined with calcium.
| Inspection items | Liquid index | Solid index |
| appearance | Yellow to reddish brown liquid | Light yellow to yellow powder |
| Solid content % | ≥30.0 | -- |
| Density (20 ℃) g/cm3 | ≥1.15 | -- |
| Moisture % | -- | ≤7.0 |
| Ultimate viscosity (30 ℃)dL/g | 0.030-0.060 | 0.030-0.060 |
| PH value (10g/L solution) | 3.0-7.0 | 3.0-7.0 |
| calcium content | ≥3.6 | ≥12.0 |
| Bulk density g/cm3 | -- | 0.25-0.55 |
Note: All specifications of Calcium Polyaspartate (PASP-Ca, CAS 10389-09-0) comply with relevant national and international standards. Customized specifications can be provided based on the specific application needs of different fields.
Calcium Polyaspartate (PASP-Ca), with the CAS number 10389-09-0, is a water-soluble, biodegradable polymer and the calcium salt of polyaspartic acid. It is synthesized through green polymerization using natural aspartic acid as the raw material, with no toxic or harmful additives added during the production process. Unlike traditional calcium supplements (such as calcium carbonate and calcium phosphate) and chemical chelating agents, PASP-Ca offers good biocompatibility, high calcium bioavailability, and complete biodegradability, making it widely applicable in multiple fields that require safe and efficient calcium supply or chelation.
- 100% biodegradable (biodegradation rate ≥70% within 28 days, complying with the OECD 301B standard) and phosphorus-free, meeting the environmental and safety standards of the EU REACH, US FDA, and China.
- High calcium bioavailability (up to 85% absorption rate in both the human body and crops), significantly higher than traditional inorganic calcium supplements, which reduces calcium waste.
- Dual functions of calcium supplementation and chelation: it can chelate trace elements (such as iron, zinc, and magnesium) while supplying calcium, thereby improving the utilization rate of nutrients.
- Mild performance, non-toxic, non-irritating, and non-corrosive, making it suitable for food, pharmaceutical, cosmetic, and agricultural applications with strict safety requirements.
- Stable performance in a wide pH range (5.0~10.0) and normal temperature environments, so it is not easy to decompose or lose efficacy during processing and storage.
Calcium Polyaspartate (PASP-Ca, CAS 10389-09-0) is used as a food-grade calcium supplement and chelating agent, suitable for various food products—especially those requiring high calcium bioavailability:
- Calcium-Fortified Foods: It is added to milk, yogurt, soy milk, bread, biscuits, and beverages to supplement calcium. It has a high absorption rate, does not affect the taste and texture of food, and causes no precipitation.
- Functional Foods: It is used in health foods for infants, the elderly, and pregnant women as a safe and efficient calcium supplement, helping to improve bone health and prevent calcium deficiency.
- Food Preservatives & Stabilizers: As a chelating agent, it can chelate metal ions (such as iron and copper) in food, prevent food oxidation and discoloration, extend the shelf life of food, and maintain food quality. It should be noted that PASP-Ca is a calcium supplement and chelating agent, not a therapeutic product, and its efficacy should not be overstated.
As a green calcium supplement and fertilizer synergist, PASP-Ca is widely used in crop planting, suitable for various crops (grains, fruits, vegetables) and soil types:
- Crop Calcium Supplement: The chelated calcium in PASP-Ca is easily absorbed by crop roots and leaves, preventing calcium deficiency diseases (such as blossom-end rot in tomatoes and bitter pit in apples), and improving crop quality and yield.
- Fertilizer Synergist: When mixed with nitrogen, phosphorus, potassium fertilizers, and trace element fertilizers, it can chelate nutrients, improve fertilizer utilization rate, reduce nutrient loss, and alleviate soil compaction.
- Soil Improvement: It adjusts soil pH, improves soil structure, and enhances soil water and fertilizer retention capacity. It is particularly suitable for acidic and alkaline soils, promoting crop root development.
PASP-Ca (CAS 10389-09-0) is used as a pharmaceutical-grade calcium supplement and drug carrier, leveraging its biocompatibility and safety:
- Calcium Supplement Drugs: It is used in the production of oral calcium supplements (tablets, capsules, oral liquids) for the prevention and auxiliary treatment of calcium deficiency diseases (such as osteoporosis and rickets). It has a high absorption rate and mild performance, making it suitable for long-term use.
- Drug Carrier: As a sustained and controlled release carrier for drugs, it can improve the solubility and bioavailability of insoluble drugs and reduce the toxic and side effects of drugs, making it widely used in the research and development of sustained and controlled release preparations.
It is used as a calcium supplement, humectant, and chelating agent in cosmetics and personal care products:
- Skin Care Products: Added to facial masks, lotions, creams, and serums, it can supplement calcium to the skin, enhance skin barrier function, improve skin elasticity and luster, and has a mild moisturizing effect with no irritation to sensitive skin.
- Hair Care Products: Used in shampoos and conditioners, it can chelate metal ions in water, prevent hair discoloration and dryness, and improve hair softness and smoothness.
- Oral Care Products: Added to toothpaste and mouthwash, it can supplement calcium to teeth, enhance tooth enamel, and prevent tooth decay, with good compatibility with other oral care ingredients.
- Feed Industry: Used as a feed additive for livestock and poultry, it supplements calcium for animals, improves bone development and production performance (such as eggshell quality in laying hens), with a high absorption rate and no side effects.
- Water Treatment: As a green chelating agent, it can chelate metal ions in water, prevent scaling and corrosion, and is suitable for low-hardness water treatment scenarios (such as drinking water treatment), avoiding environmental pollution.
- Textile Industry: Used as a chelating agent and dispersant in textile printing and dyeing, it improves the uniformity of dyeing and prevents dye precipitation, ensuring the color fastness of textiles.
Compared with traditional inorganic calcium, PASP-Ca forms a stable chelate structure. This structure prevents the formation of insoluble calcium salts in the human body or soil, thereby improving calcium absorption and utilization. This advantage is particularly evident in scenarios where calcium absorption is challenging, such as for the elderly, infants, and in alkaline soil.
As a phosphorus-free and fully biodegradable polymer, it does not cause water eutrophication or soil pollution. It can be naturally degraded into aspartic acid and calcium ions, both of which are non-toxic and harmless. It meets the environmental requirements of various countries and regions, helping users avoid environmental risks and market access barriers.
It combines calcium supplementation and chelation. It not only supplies calcium to the human body, crops, or products but also chelates trace elements, which improves the stability and efficacy of the overall system. It is applicable to food, agriculture, pharmaceuticals, cosmetics, and other fields, reducing the need for multiple additives.
It does not irritate human skin, mucous membranes, or crop roots, and has no toxic side effects when used at the recommended dosage. It is suitable for food-grade and pharmaceutical-grade applications, and can be used in the production of green and organic agricultural products.
It can be freely mixed with most additives, fertilizers, pesticides, and pharmaceutical raw materials without precipitation or loss of efficacy. It remains stable during high-temperature processing (≤80℃ for long-term use) and normal storage, ensuring consistent product quality.
Although its unit price is slightly higher than that of traditional inorganic calcium, its high absorption rate and dual functions reduce the overall usage amount and comprehensive cost. It does not require additional auxiliary agents to improve absorption, which simplifies the formula and production process.
1. Low absorption rate of traditional calcium supplements, leading to calcium waste and poor results (e.g., calcium precipitation in the human body, low calcium utilization rate in crops).
Solution: Calcium Polyaspartate (CAS 10389-09-0) has high bioavailability. It can be directly absorbed without conversion in the human body or soil, improving calcium utilization rate by 30~50% compared with traditional calcium supplements and avoiding waste.
2. Environmental pollution caused by non-biodegradable chelating agents or calcium supplements, leading to failure in environmental inspections or market rejection.
Solution: PASP-Ca is 100% biodegradable and phosphorus-free. It does not pollute water or soil, meets international environmental standards, and helps users pass environmental inspections and enter the global market smoothly.
3. Irritation of traditional calcium supplements to the stomach and intestines (e.g., calcium carbonate causes bloating and acid reflux) or damage to crop roots.
Solution: PASP-Ca has a mild pH value (close to neutral). It does not irritate the human stomach and intestines, nor does it damage crop roots, making it suitable for long-term use and application in sensitive scenarios (such as for infants, the elderly, and seedling-stage crops).
4. Poor compatibility of calcium supplements with other raw materials, leading to precipitation, discoloration, or loss of efficacy in products.
Solution: PASP-Ca has excellent compatibility with most food additives, pharmaceutical raw materials, fertilizers, and pesticides. No precipitation or chemical reactions occur when mixed, ensuring the stability and efficacy of the final product.
5. High comprehensive cost due to the need for additional auxiliary agents to improve calcium absorption.
Solution: PASP-Ca itself has a high absorption rate, so there is no need to add auxiliary agents (such as vitamin D3 in human calcium supplements). This simplifies the formula, reduces the types of raw materials, and lowers the comprehensive production cost.
6. Single function of calcium supplements, which can only supply calcium and cannot meet the needs of trace element chelation or nutrient synergism.
Solution: PASP-Ca has dual functions of calcium supplementation and chelation. It can chelate trace elements (iron, zinc, magnesium) while supplying calcium, improving the overall nutrient utilization rate and meeting the multi-functional needs of different fields.
Liquid Product: Packed in 25kg food-grade plastic barrels or 250kg IBC tanks; customized packaging (such as 10kg or 100kg barrels) is available upon request for small-batch users.
Solid Product: Packed in 20kg food-grade plastic woven bags (with an inner polyethylene film bag) to prevent moisture absorption.
Labeling: Each package is clearly labeled with the product name (Calcium Polyaspartate), CAS number (10389-09-0), specification, net weight, production date, shelf life, manufacturer, and safety instructions, in line with international labeling standards.
Store in a cool, dry, and well-ventilated warehouse, avoiding direct sunlight and high temperatures (storage temperature: 5~35℃); do not store outdoors or in humid environments. Keep the package sealed to prevent moisture absorption (for solid products) or leakage (for liquid products); avoid mixing with strong acids, strong alkalis, and oxidants.
Shelf Life: 12 months for liquid products and 24 months for solid products when stored according to the above requirements; do not use if the product is discolored, deteriorated, or has sediment after expiration.
Transportation: Transport as non-dangerous goods; avoid violent collision, sun exposure, and rain during transportation; handle with care to prevent package damage and leakage. For food-grade and pharmaceutical-grade products, transport in a clean and pollution-free environment.
During use, it is still important to avoid inhaling dust or coming into contact with the skin and eyes. If accidentally touched, rinse immediately with plenty of water.
Due to its strong hygroscopicity, it should be sealed during storage to prevent moisture and clumping, which may affect its performance and effectiveness.
Liquid PASP-Ca (30%): Add to beverages, milk, and yogurt at a dosage of 0.5~2.0% (v/v), and stir uniformly at 20~40℃ to ensure complete dissolution without precipitation.
Solid PASP-Ca: Add to bread, biscuits, and health food tablets at a dosage of 0.3~1.0% (w/w), mix uniformly with other raw materials before processing, and proceed with the normal production process.
Note: Adjust the dosage according to the calcium content requirements of the final product; do not use it together with strong acid or strong alkali ingredients, as this may affect calcium stability.
Foliar Spraying: Dilute liquid PASP-Ca to 300~500 times (300~500 mg/L), and spray on crop leaves during the seedling stage, flowering stage, and fruiting stage. Apply once every 7~10 days, for a total of 2~3 times. Avoid spraying at high noon temperatures, and spray on the back of leaves for better absorption.
Root Irrigation: Dilute liquid PASP-Ca to 400~600 times, and apply through drip irrigation or flood irrigation. Use 1~2 times per crop growth cycle, with a dosage of 10~15 kg per mu (1 mu ≈ 0.067 hectares), which helps with root absorption and soil improvement.
Fertilizer Mixing: Mix 100~200g of solid PASP-Ca with 50kg of compound fertilizer or trace element fertilizer, and apply as base fertilizer or topdressing. This can improve fertilizer utilization rate while supplementing calcium.
Oral Calcium Supplements: For tablets or capsules, use 50~100mg of solid PASP-Ca per unit (calculated by calcium content). Mix with pharmaceutical excipients (such as lactose and starch), and press into tablets or fill into capsules according to the normal pharmaceutical production process.
Oral Liquids: Dilute liquid PASP-Ca to an appropriate concentration (calcium content 50~100mg/10mL), add flavoring agents and preservatives, stir uniformly, and fill into bottles after sterilization.
Note: The dosage must comply with pharmaceutical standards and doctor's advice; do not use it together with other calcium supplements to avoid excessive calcium intake.
Skin Care Products: Add 0.1~0.5% of solid PASP-Ca or 0.5~1.0% of liquid PASP-Ca to the cosmetic formula. Mix uniformly with other ingredients (such as humectants and emulsifiers) at 40~50℃, and cool to room temperature to form the final product.
Hair Care Products: Add 0.2~0.8% of liquid PASP-Ca to shampoos or conditioners, and stir uniformly with surfactants and other ingredients to ensure no precipitation or turbidity.
Note: Ensure the product meets cosmetic-grade standards before use; avoid using it in products with pH < 5.0 or pH > 8.5.
Conduct a small-scale test before large-scale use of Calcium Polyaspartate (PASP-Ca, CAS 10389-09-0) to determine the optimal dosage according to the specific application scenario;
Avoid contact with strong acids, strong alkalis, and oxidants, and store separately from incompatible substances to maintain product performance;
Operate with gloves during use; if it comes into contact with skin or eyes, rinse with plenty of clean water immediately;
Keep away from children and pets, and do not eat or drink;
Do not overstate the product's efficacy, especially in food and pharmaceutical applications, to comply with relevant regulatory requirements.
Whether you're developing nutrient-rich foods, premium health supplements, or sustainable agricultural solutions, calcium polyaspartate delivers superior performance and proven results.
Contact us today to request a sample, discuss custom formulations, or get a technical data sheet tailored to your industry needs.
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Our sales and technical teams can work with you to understand your requirements and recommend the most appropriate product based on your application and conditions.
Yes, please refer to the safety data sheets provided for each product for detailed handling and safety instructions.
Yes, upon request and subject to certain conditions, we can provide samples for your evaluation and testing.
Yes, we have a dedicated technical support team available to assist customers with any questions or issues related to the use of our products.
We have strict quality control processes in place, including raw material inspection, in-process monitoring, and final product testing to ensure consistent quality.
